研究業績
2024
Nguyen LM, Kanda A, Kamioka Y, Tokuhiro K, Kobayashi Y, Yun Y, Bui DV, Chu HH, Le NKT, Suzuki K, Mitani A, Shimamura A, Fukui K, Dombrowicz D, Iwai H.
Mouse eosinophil-associated ribonuclease-2 exacerbates the allergic response.
Allergy. 2024 Feb 23. doi: 10.1111/all.16061. Online ahead of print.
2023
Kamioka Y, Ueda Y, Kondo N, Tokuhiro K, Ikeda Y, Bergmeier W, Kinashi T.
Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow.
Cell Rep. 2023 Jun 1;42(6):112580.
Tanaka H, Matsushita H, Tokuhiro K, Fukunari A, Ando Y.
Ingestion of Soybean Sprouts Containing a HASPIN Inhibitor Improves Condition in a Mouse Model of Alzheimer's Disease.
Biology (Basel). 2023 Feb 16;12(2):320.
Morohoshi A, Miyata H, Tokuhiro K, Iida-Norita R, Noda T, Fujihara Y, Ikawa M.
Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility.
Sci Adv. 2023 Jan 25;9(4):eade7607.
2022
Tanaka H, Tokuhiro K.
A Haspin promoter element induces tissue-specific methylation of a transcription region and the regulation of gene expression in mouse ova.
Cell J. 2022 Sep 12;24(9):552-554.
Tanaka H, Nishida-Fukuda H, Wada M, Tokuhiro K, Matsushita H, Ando Y.
Inhibitory Effect of the HASPIN Inhibitor CHR-6494 on BxPC-3-Luc, A Luciferase-Expressing Pancreatic Cancer Cell Line.
Cell J. 2022 Apr;24(4):212-214.
Oyama Y, Miyata H, Shimada K, Fujihara Y, Tokuhiro K, Garcia TX, Matzuk MM, Ikawa M.
CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice.
Asian J Androl. 2022 May-Jun;24(3):266-272.
2021
Nishida-Fukuda H, Tokuhiro K, Ando Y, Matsushita H, Wada M, Tanaka H.
Evaluation of the antiproliferative effects of the HASPIN inhibitor CHR-6494 in breast cancer cell lines.
PLoS One. 2021 Apr 14;16(4):e0249912.
2020
Aoki Y, Tsujimura A, Kaseda K, Okabe M, Tokuhiro K, Ohta T, O'Bryan MK, Okuda H, Kitamura K, Ogawa Y, Fujiki T, Wada M, Horie S, Nishimune Y, Tanaka H.
Haprin-deficient spermatozoa are incapable of in vitro fertilization.
Mol Reprod Dev. 2020 May 87(5):534-541.
2019
Vogt EJ, Tokuhiro K, Guo M, Dale R, Yang G, Shin SW, Movilla MJ, Shroff H, Dean J.
Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis.
Nat Commun. 2019 May 22;10(1):2271.
2018
Ahmed SM*, Nishida-Fukuda H*, Li Y, McDonald WH, Gradinaru CC, Macara IG.
(*:contributed equally)
Exocyst dynamics during vesicle tethering and fusion.
Nat Commun. 2019 May 22;10(1):2271.
Tokuhiro K, Dean J.
Glycan-Independent Gamete Recognition Triggers Egg Zinc Sparks and ZP2 Cleavage to Prevent Polyspermy.
Dev Cell. 2018 Sep 10;46(5):627-640.